List of artists with only one Hot 100 single, and that song reached the top ten (since 1978):
- Oleta Adams - "Get Here" (#5, 1991)
- Tatyana Ali - "Daydreamin'" (#6, 1998)
- Aloe Blacc* - "The Man" (#8, 2014)
- Baauer - "Harlem Shake" (#1, 2013)
- Biz Markie - "Just A Friend" (#9, 1990)
- BlocBoy JB - "Look Alive" ft. Drake (#5, 2018)
- Boys Club - "I Remember Holding You" (#8, 1989)
- Buckner & Garcia - "Pac Man Fever" (#9, 1982)
- Rocky Burnette - "Tired Of Toein' The Line" (#8, 1980)
- The Calling - "Wherever You Will Go" (#5, 2002)
- Deep Blue Something - "Breakfast At Tiffany's"
- Gary Numan - "Cars" (#9, 1980)
Runners-up (missed the top ten, but had long chart runs)
- American Authors - "Best Day Of My Life" (#11, 2014)
- Jann Arden - "Insensitive" (#12, 1996)
- James Arthur - "Say You Won't Let Go" (#11, 2017)
- Awolnation - "Sail" (#17, 2013)
- Tal Bachman - "She's So High" (#14, 1999)
- Boys Don't Cry - "I Wanna Be A Cowboy" (#12, 1986)
* Appeared as a featured artist on other Hot 100 songs